Yes, with the Price Per Customer Magento 2 Extension, offering separate pricing to different customers or customer groups for a single product is possible. Based on customer attributes, you can create custom price rules.

Follow below steps to set different prices for same product in your Magento 2 store.

Step 1. Log in to Admin Panel.

Step 2. Navigate to Stores > Settings > Configuration.

Step 3. Under Catalog, select catalog.

Step 4. Expand the “Price” section.

Step 5. Then in the tab "Price", set price scope to Website instead of global.

Step 6. On the product edit page, you can then set the scope on the upper left side to your website and then enter a per website price.

Step 7. Save the configuration.

Read this guide on How to Configure Price Per Customer in Magento 2 to setup this extension.

Here are the few more resource to help you get most out of this Magento 2 Price Per Customer Extension.

• Magento 2 Customer Group Pricing: A Complete Guide On Tier Price Rules
• How to Implement Customer-Specific Pricing in Magento 2
• Learn How Price Per Customer Extension Helps You Build Customer Relation